New research shows that drug-resistant bacteria can make the journey from the digestive tract to the lungs, raising the probability of infection.
, non-resistant bacteria in the gut and lungs were killed. This made it possible for antibiotic-resistantThen, the study found that, during antibiotic therapy, Pseudomonas translocated from the gut to the patient's lungs, developing even higher levels of drug resistance.
in hospitals. Therefore, it's crucial for patients who are already at risk to stop the germs from spreading to other crucial organs like the lung. It can be challenging to pinpoint the source of the bacteria that cause these dangerous illnesses, though.This work demonstrates how the gut microbiome might serve as a reservoir for AMR infections that can move to the lungs and potentially cause deadly diseases like pneumonia.
To gauge how long the patient had been infected with Pseudomonas, researchers examined them periodically while in the hospital. By building a time-calibrated bacterial family tree, they could look at how the infection changed over time, how it spread, and where it was. There was also a lot of genetic diversity in the gut, which supports the idea that the microbiome may be a source of AMR.
AMR strategies frequently concentrate on minimizing infection from outside sources, but it's equally essential to comprehend how AMR can arise and spread inside a patient.
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