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In a study published in 2023, scientists found that using sleeping pills to get some shut-eye could reduce the build-up of toxic clumps of proteins in fluid that washes the brain clean every night.Though only short and involving a small group of healthy adults, the study is an interesting demonstration of the link between sleep and the molecular markers of Alzheimer's disease.
Researchers think promoting sleep could be one avenue to stave off Alzheimer's disease, by allowing the sleeping brain to flush itself of leftover proteins and the day's other waste products. There were no differences in sleep between the groups, and yet amyloid-beta concentrations were reduced by between 10 and 20 percent with a dose of suvorexant usually prescribed for insomnia, compared to a placebo.
However, this effect was only seen with some forms of tau, and tau concentrations sprung back up within 24 hours of taking the sleeping pill.testing sleeping pills for months could possibly measure a lasting effect on protein levels .under intense scrutiny
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