has shown that the Omicron wave in the Western Cape was much less deadly than previous waves, owing to vaccination, high rates of past infection in the community, and reduced risk of severe disease and death owing to the variant itself.
The study was led by Prof Mary-Ann Davies, director of the Centre for Infectious Disease Epidemiology & Research at the University of Cape Town, working in collaboration with 46 others from the Western Cape department of health; the national department of health; the National Health Laboratory Service; the Universities of Cape Town, Stellenbosch, the Witwatersrand, and KwaZulu-Natal; the Francis Crick Institute; and Imperial College London.
When adjusting for vaccination, there was a 59% reduced risk of death and 28% reduced risk of severe disease from infection during the fourth wave compared to previous waves. This indicates that vaccination is associated with a strongly reduced risk of death and severe disease.
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