The Sisonke study builds on the Ensemble trial and started in mid-February — once the Ensemble study’s results had been announced.
But any hospital can’t just become a vaccination site — a facility needs to be Covid compliant and have enough fridges to store jabs at the correct temperature during the day. In the Sisonke study, the researchers are responsible for the storage of jabs at the vaccination sites. They also have to supervise the preparation of shots at the vaccination venues. The J&J vaccines are stored at research sites in -20? freezers and are then thawed overnight and transported to all the other vaccination centres. At the centres, the vaccines are prepared and drawn up into syringes under the supervision of trained pharmacists.
“We’ve done that in Ixopo [in the southern KwaZulu-Natal Midlands], and booked people into hotels for a week and managed to complete all vaccinations within that week,” says Garrett.This will include mobile outreach teams that can serve smaller hospitals and clinics in more remote areas.William Brumskine from the Aurum Institute is a clinical research site leader for the Sisonke study in Rustenburg.
The day to day running of a site therefore needs researchers, pharmacists, clinic floor and vaccination coordinators to all speak to each so that the opening of vials are co-ordinated and jabs aren’t wasted. If there are punctured vials left after all scheduled and walk-in vaccinations have been done, health workers working at a site who haven’t yet been vaccinated, are called in for unscheduled appointments and get vaccinated with the left-over stock.Yes, according to Garrett, Brumskine and the Western Cape health department, the Sisonke sites may also be used for South Africa’s wider, national roll-out.
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