Pfizer, Moderna vaccines effective against Indian variants: study

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The lab-based study was carried out by the NYU Grossman School of Medicine and NYU Langone Center and is considered preliminary because it has not yet been published in a peer-reviewed journal.

WASHINGTON - The Pfizer and Moderna COVID-19 vaccines should remain highly effective against two coronavirus variants first identified in India, according to new research carried out by US scientists.

They then exposed these samples in a lab to engineered pseudovirus particles that contained mutations in the "spike" region of the coronavirus, which were particular to either the B.1.617 or B.1.618 variants, first found in India.The engineered pseudovirus particles contained an enzyme called luciferase, which fireflies use to light up. Adding it to the pseudovirus makes it possible to tell how many cells are infected, based on light measurements.

"There's enough that do work that we believe that the vaccines will be highly protective," he added, because the overall levels remain well above those found in samples taken from people who recovered from infection with earlier unmutated virus.

 

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