Omicron may have a higher rate of asymptomatic carriage, say experts

2022/01/11 12:14:00

Preliminary findings from two clinical trials in SA suggest that Omicron may have a much higher rate of asymptomatic 'carriage' than earlier variants of Covid-19.

Preliminary findings from two clinical trials in SA suggest that Omicron may have a much higher rate of asymptomatic 'carriage' than earlier variants of Covid-19.

Preliminary findings from two clinical trials in SA suggest that Omicron may have a much higher rate of asymptomatic 'carriage' than earlier variants of Covid-19.

SAMRC president Prof Glenda Gray said the findings are preliminary — part of a paper posted at medrxiv.org before peer review and publication — but they appear to be in line with the bigger picture coming together about Omicron’s high transmissibility.

“The larger studies were designed to analyse data at the intersection of Covid-19, vaccines, and people living with HIV, but they also are giving us useful information about omicron and how its spread differs from those of previous variants of concern,” she said.

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23 hours ago SAMRC president Prof Glenda Gray said the findings are preliminary — part of a paper posted at medrxiv.Coronavirus watch At the peak of the Omicron surge, the number of beds filled with infected patients was half of that in the earlier period, and 63% of Omicron patients were hospitalised for other reasons, with the virus only detected by mandatory tests.Citing"uncertainty" surrounding the new coronavirus variant, the Recording Academy indefinitely postponed the music awards, while Sundance organizers said the festival would go virtual with infection numbers reaching new highs.09 January 2022 - 21:44 Fergal O'Brien and Chris Reiter Demonstrators march near the Louvre Museum during a protest against vaccination pass rules and vaccinations to control the spread of Covid-19 in Paris, France, January 8 2022.

org before peer review and publication — but they appear to be in line with the bigger picture coming together about Omicron’s high transmissibility. “The larger studies were designed to analyse data at the intersection of Covid-19, vaccines, and people living with HIV, but they also are giving us useful information about omicron and how its spread differs from those of previous variants of concern,” she said.. Dr Nigel Garrett, head of vaccine and HIV pathogenesis research at the Centre for the Aids Programme of Research in SA, said the studies were initiated because sub-Saharan Africa has been hit hard by both HIV and the Covid-19 pandemic. And in the UK, official data shows one in 15 people in England were infected with the virus in 2021's final week. “Ubuntu and Sisonke will provide important data on safety, dosage and effectiveness of vaccines, but they already are helping us better understand the way this virus can change and how those changes affect transmission and severity. with unprecedented speed, peaking within four weeks,” the researchers said. It is critical that we know how Omicron and other variants spread among those who are immunocompromised as well as those who are not,” he said. In the UK, Johnson accused anti-vaxxers of spreading “nonsense”.

Of the initial 230 participants who underwent screening for the Ubuntu study between December 2 and 17, 31% tested positive for the coronavirus. But if the pattern seen in SA “continues and is repeated globally . The new decree obliges people over 50 who do not work to get vaccinated, and those who do work to obtain a vaccine pass -- which effectively covers all over-50s. The researchers said this is in stark contrast to the positivity rate pre-Omicron, which ranged from less than 1% to 2.4%.. The sub-study of the Sisonke trial found that the mean asymptomatic carriage rate of 2. The government is currently debating replacing the current health pass -- which contains proof of vaccination, a negative test or recent recovery -- with a"vaccine pass" for which only people with full vaccination qualify.6% during the Beta and Delta outbreaks rose to 16% during the Omicron period. Meanwhile, researchers believe they have discovered an important way to identify SARS-CoV-2 variants that are likely to spread. About 77% of the population is fully vaccinated, according to government figures, putting him squarely on the side of the majority.

The Sisonke study included 577 subjects previously vaccinated with the AD26.SARS. The original, or wild, version of the virus had 45 unique so-called 9-mers, the researchers reported on Thursday on medRxiv review. Around five million people in France remain unvaccinated.CoV.2 vaccine, with results suggesting a high carriage rate even in those known to be vaccinated. The currently dominant Omicron variant has 295. “We are not yet able to determine how vaccination affects asymptomatic infection and spread,” said Prof Linda-Gail Bekker, professor of medicine and director of the Desmond Tutu HIV Centre at the University of Cape Town. Like mainland China, Hong Kong has maintained some of the world's harshest controls -- including weeks-long quarantine periods, targeted lockdowns and mass testing.  Neighbouring Italy on Wednesday made shots compulsory for people over 50, though the fine of €100 for non-compliance has been kept deliberately low.

“We further need to devise strategies for rapid detection of asymptomatic carriage, particularly in long-term care facilities and hospitals, where transmission to high-risk populations may occur. The spike is the target of most current Covid-19 vaccines and antibody treatments. “Our data also strongly support the need to reach global equity with primary vaccination and to develop second-generation vaccines that may be even more protective against acquisition.” TimesLIVE READ MORE: . Because IHU has not circulated widely outside of France, he said, populations have not acquired immunity to it, and variants that have yet to emerge in other places may find it “useful” to develop some of the same 9-mer mutations. READ: Discovery Health reports on Omicron in SA The struggle to square health measures with major sporting events also hit Australia, where controversy is mushrooming after the country canceled the entry visa of tennis world number one Novak Djokovic over a paperwork snag.