What Is Dostarlimab, the Drug Used in ‘Unprecedented' Cancer Trial?

6/7/2022 12:30:00 AM

A newly disclosed cancer study had 'unprecedented' and 'unheard-of' results, and now all eyes are on dostarlimab, the GlaxoSmithKline drug used to achieve complete remission in the trial.

A newly disclosed cancer study had 'unprecedented' and 'unheard-of' results, and now all eyes are on dostarlimab, the GlaxoSmithKline drug used to achieve complete remission in the trial.

A newly disclosed cancer study had “unprecedented” and “unheard-of” results, and now all eyes are on dostarlimab, the GlaxoSmithKline drug used to achieve complete remission in the trial. Developed by a biotech company out of Massachusetts called Tesaro before being acquired by GlaxoSmithKline in 2019, dostarlimab is also known by the brand name Jemparli. First approved in the United States…

The term became more widely known in the last two years as a variety of monoclonal antibodies came out to treat COVID-19.Register now for FREE unlimited access to Reuters.Patients with a particular kind of cancer and a particular kind of mutation received a new therapy called dostarlimab and had results not seen in a cancer trial before Published 5 hours ago Updated 7 mins ago NBC 7 A small NYC-led cancer trial has achieved a result reportedly never before seen - the total remission of cancer in all of its patients.It's not a cure.

Dostarlimab is specifically designed to block a particular protein involved in cancer cells called PD-1.In the Memorial Sloan Kettering trial with rectal cancer, all of the patients' tumors also had a feature known as mismatch repair deficiency.The standard treatment in many countries, however, is an anti-VEGF antibody like Roche's (ROG.What Is Mismatch Repair Deficiency? Cells that have mutations that keep them from fixing mistakes when DNA is copied are said to have"mismatch repair deficiency." Having mismatch repair deficiency can be associated with cells becoming cancerous.In the trial of more than 800 patients with metastatic colon cancer and the "wild-type," or natural non-mutated, RAS genes, participants received standard chemotherapy plus either Vectibix or Avastin.Copyright NBC New York.The drug is Enhertu, an antibody-chemotherapy combo given by IV.

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Cancer research: Amgen drug extends survival in some inoperable colon cancersThe following are summaries of some of the cancer research advances being presented the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

Small Cancer Trial Delivers ‘Unheard-of' Result: Complete Remission for EveryoneA small NYC-led cancer trial has achieved a result reportedly never before seen – the total remission of cancer in all of its patients. To be sure, the trial — led by doctors at Memorial Sloan Kettering and backed by drug maker GlaxoSmithKline — has only completed treatment of 12 patients, with a specific cancer in its early stages and… It’s been out there for years they just have a pile of other medicines they had to sell first. Elementary my dear Mr. Watson, elementary!

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Small Rectal Cancer Study Has Remission in Every PatientA small clinical trial with 12 rectal cancer patients found remission in 100% of them, according to a new paper published in The New England Journal of Medicine. 12? that is worthless absent to the 12 participants Another 'cancer cure' study for which we will surely have to wait '10 years' to prove it well. It's the story I've heard for years, they find something that heals and you have to wait 10 years, which later are forever because the treatments never appear. Saw the endoscopies here on tt of the patients ,please do share again if you have