Scientists were a step closer to an effective treatment for Ebola after two drugs in a clinical trial were found to significantly boost survival rates, the US health authority co-funding the research said Monday.
REGN-EB3 and mAb114 "are the first drugs that, in a scientifically sound study, have clearly shown a significant diminution in mortality for people with Ebola virus disease," Anthony Fauci, director of the NIH's National Institute of Allergy and Infectious Diseases, told AFP. Fauci explained that the trial was designed to include 725 people, but was halted by an independent board when it had enrolled 681 people because at that point, one of the drugs, REGN-EB3 by Regeneron, reached a critical threshold in success, while mAb114 was not far behind.
The NIH, Democratic Republic of Congo health authorities and the World Health Organization hailed the "extraordinary team of individuals who have worked under extremely difficult conditions to carry out this study," as well as the patients and their families.
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