nko, a crop health company supported by the Gates Foundation, announced Tuesday that it has signed a multi-year partnership with Syngenta Crop Protection to design sustainable and safe solutions to combat pests, weeds and diseases for farmers across the world in a way that reduces development and production time.
To better fight pests and disease, Enko has developed a target-based approach. It starts by studying a particular pest, examining it for proteins or cell functions that might be able to be inhibited by one of the thousands of chemicals it has in its DNA-encoded library. Its machine learning and AI algorithms help its researchers gauge how well the chemicals in the library work against the intended target.
Enko looked to partner with Syngenta in order to leverage the latter’s technology to “bring speed in developing new and novel chemistries quickly to the pipeline.” Developing new pesticides or treatments for agriculture typically takes 10-12 years, but with this new partnership, these companies hope to cut that time in half. One advantage is that their technologies can help determine both safety and efficacy earlier in the development process, hastening the speed to commercialization.
Heard says her company has been inspired by the latest drug discovery and development approaches in the pharmaceutical industry, which have become more specific and selective so new drugs can hit their targets. “We looked at that and thought there are tools that are being used in the pharmaceutical industry today that are aiding with the things that would yield more efficacious and safer products for crop protection,” she adds.
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