Study tried to replicate 50 cancer experiments and fell short more than half the time

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An eight-year project to carefully repeat early but influential lab experiments in cancer research has reached a disappointing conclusion.

Eight years ago, a team of researchers launched a project to carefully repeat early but influential lab experiments in cancer research.

“The truth is we fool ourselves. Most of what we claim is novel or significant is no such thing,” said, a cancer doctor and researcher at UC San Francisco, who was not involved in the project. , president of the National Academy of Sciences. Researchers lose prestige if their results don’t hold up to scrutiny, she said.But for cancer patients, it can raise false hopes to read headlines of a mouse study that seems to promise a cure “just around the corner,” Prasad said. “Progress in cancer is always slower than we hope.”

 

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