Study: Stimulant ADHD Medication Relatively Safe and Effective for Older Adults

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A new study found that older adults with ADHD largely experience symptom improvement when taking a low dose of stimulant medication, which is well tolerated and does not cause clinically significant cardiovascular changes.

use of antihypertensive drugs before starting medicine for ADHDPearson’s correlation was used to measure the correlation between dosage and differences in weight, systolic blood pressure, diastolic blood pressure, and heart rate.

Close to 30% of adults in the study had a pre-existing cardiovascular risk profile. Approximately 65% of participants reported positive responses to low-dose stimulant medication. 42% of patients quit the medication due to nonresponse or side effects including anxiety and, cardiovascular complaints, and sleep problems. The study lacked a control group and was observational in nature, so no firm conclusions can be drawn as to the effectiveness of the stimulants used.

, even among those with increased cardiovascular risk profiles. Patients experienced significant and clinically relevant improvement of their ADHD symptoms using stimulants, comparable with what is found among younger age groups.Michielsen, M., Kleef, D., Bijlenga, D., Zwennes, C., Dijkhuizen, K., Smulders, J., … Kooij, J. J. S. . Response and Side Effects Using Stimulant Medication in Older Adults With ADHD: An Observational Archive Study.

 

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