Regeneron antibody therapy helps Covid patients lacking antibodies – study

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Regeneron antibody trial results translate into six fewer deaths for every 100 patients lacking natural antibodies, with investigators confident in therapy's benefit

The Regeneron Pharmaceuticals company logo is seen on a building at the company's Westchester campus in Tarrytown, New York, US, September 17, 2020.

It found that the antibody therapy reduced by a fifth the 28-day mortality of people admitted to hospital with Covid-19 whose immune system had not mounted an antibody response, known as seronegative. "People have been very, very sceptical, that any treatment against this particular virus would work by the time people get in hospital," Martin Landray, the joint chief investigator on the trial, told reporters.The treatment also shortened the hospital stay of those who were seronegative and reduced their chances of needing a mechanical ventilator, Landray said.

The RECOVERY trial also showed the steroid dexamethasone and Roche's arthritis drug Actemra cut deaths in hospitalised patients.

 

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