Ramp Atlas: facilitating tissue and cell-specific ramp sequence analyses through an intuitive web interface

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Researchers develop online portal to show how biases in RNA sequences affect geneexpression universityofky

Heat map of percentage of SARS-CoV-2 ramp sequences shared between tissues. The percentage of ramp sequences in SARS-CoV-2 genes that are present in both tissues being compared. Calculated using the consensus dataset. The redder the tissue comparison, the smaller the percentage of ramp sequences were present in both tissues. The bluer the comparison, the higher percentage of shared ramp sequences.Heat map of percentage of SARS-CoV-2 ramp sequences shared between tissues.

Users can interactively query Tableau charts on the ‘SARS-CoV-2’ page of The Ramp Atlas to thoroughly explore ramp sequences within the SARS-CoV-2 genome as well as in seven human entry factors for SARS-CoV-2. An interactive heat map at the top of the page shows the percentage of SARS-CoV-2 ramp sequences that are shared between different tissues in the consensus dataset.

. To run ExtRamp Online, users can either paste a FASTA formatted gene header and sequence into a text box or upload a small FASTA file of coding sequences. The FASTA file must contain only coding sequences , and the coding sequences must contain all codons from the start codon to the stop codon, inclusively.

 

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