Prior Psychological Distress Tied to 'Long COVID' Conditions

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Experiencing psychological distress prior to becoming infected with SARS-CoV-2 is tied to an increased risk for long COVID conditions, new research suggests. MedTwitter

In addition, participants who had experienced at least two types of distress prior to infection were at nearly 50% increased risk for post–COVID conditions .

Senior author Andrea Roberts, PhD, senior research scientist at the Harvard T. H. Chan School of Public Health, noted that the investigators did not examine biological mechanisms potentially underlying the association they found. Su, who was not involved with the study, was previously at the Institute for Systems Biology and has written about long COVID.

Wang pointed to past research suggesting that some patients with mental illness"sometimes develop autoantibodies that have also been associated with increased risk of long COVID." In addition, depression"affects the brain in ways that may explain certain cognitive symptoms in long COVID," she added.


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