Prior Infection Is Little Defense Against Virus Variant, Scientists Say

People wait in line at COVID-19 testing site in Times Square on Friday, Dec. 3, 2021, in New York. The omicron variant of COVID-19, which had been undetected in the U.S. before the middle of this week, had been discovered in at least five states by the end of Thursday, showing yet again how mutations of the virus can circumnavigate the globe with speed and ease.

By Thursday, omicron had been detected in 25 countries on six continents, and experts say it will soon be in every populated corner on Earth. That could mean that a world already battered by two years of pandemic and — until recently — harboring hopes for recovery is instead headed for another wave of cases.Scientists have known since early in the pandemic that the immunity gained from a coronavirus infection is not total, and probably not permanent, and that some people are reinfected.

“We believe that previous infection does not provide them protection from infection due to omicron,” said Anne von Gottberg, a microbiologist at the communicable disease institute. In fact, many crucial questions about the variant remain unanswered: Does prior infection protect against serious illness, if not against infection? Do existing vaccines provide strong immunity to it? Is the illness it causes usually milder, as some early reports have suggested?

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