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Popular Drug Does Not Alleviate Mild COVID-19 Symptoms, Study Finds

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Ivermectin, a controversial anti-parasitic drug that has been touted as a potential COVID-19 treatment, does not speed recovery in people with mild cases of the disease, according to a randomized controlled trial published Thursday in the journal JAMA. Ivermectin is typically used to treat parasitic worms in both people and animals, but scientific evidence for its efficacy against the coronavirus is thin. Some studies have indicated that the drug can prevent several different viruses from replicating in cells. And last year, researchers in Australia found that high doses of ivermectin suppressed SARS-CoV-2, the virus that causes COVID-19, in cell cultures. Such findings had spurred use of the drug against COVID-19, especially in Latin America. Sign up for The Morning newsletter from the New York Times “Ivermectin is currently being used widely,” said Dr. Eduardo López-Medina, a doctor and researcher at the Center for Pediatric Infectious Diseases in Cali, Colombia, who led the new trial. “In many countries in the Americas and other parts of the world, it’s part of the national guidelines of treating COVID.” But the drug has also proved divisive. While some scientists see potential, others suspect that effectively inhibiting the coronavirus may require extremely high, potentially unsafe doses. Health officials have also worried that people desperate for coronavirus treatments might take versions of the drug that have been formulated for pets. (It is commonly used to prevent heartworm in dogs.) “There’s been a lot of conflicting views on this, sometimes extreme conflicting views,” said Dr. Carlos Chaccour, a researcher at the Barcelona Institute for Global Health who was not involved in the new study. “I think it has become another hydroxychloroquine.” But neither the proponents nor the critics have had much rigorous data to support their views. There are few well-controlled trials of the drug’s effectiveness against COVID-19, although more are expected in the coming

Diese Schuheinlagen können Ihnen helfen, sich glücklicher, produktiver und weniger gestresst zu fühlen. Bestellen heute.Pfizer's Plant For Boosting COVID-19 Vaccine Production Has Been Rebuked For Repeat Quality Offenses: Bloomberg

Pfizer Inc’s McPherson, Kansas plant used to accelerate production of its COVID-19 vaccine was cited by federal inspectors last year for repeated quality-control violations, reports Bloomberg. The FDA inspectors visited the plant at the end of 2019 into January 2020 and found that the company released medications for sale after failing to review quality issues thoroughly that arose in routine testing.

 

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