Pfizer and its partner company BioNTech will request authorization from the Food and Drug Administration to give third doses to children approximately six months after the second dose. A phase 2/3 clinical trial found that the booster raised antibodies against the omicron variant thirty-sixfold compared to levels seen after two shots.
“These data demonstrate an increase in SARS-CoV-2 Omicron variant and wild-type strain neutralizing titers following a booster dose of the Pfizer-BioNTech COVID-19 vaccine compared to two doses,” the companies said. “These data reinforce the potential function of a third dose of the vaccine in maintaining high levels of protection against the virus in this age group.
They conducted trials of a 3 microgram dose of the COVID-19 vaccine for children under 5 but announced in December it had failed to produce a strong immune response and that adding a third dose would be necessary. The companies submitted the application for authorization of shots for this age group despite the lack of clinical trial data to back them up.Still, administering the vaccines to young children has been controversial.
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