Omicron thwarts some of the world’s most-used COVID vaccines

1/26/2022 1:48:00 AM

Inactivated-virus vaccines elicit few, if any, infection-blocking antibodies — but might still protect against severe disease.

The world’s most widely used COVID-19 vaccines provide little to no protection against infection with the Omicron variant, laboratory evidence suggests

Inactivated-virus vaccines elicit few, if any, infection-blocking antibodies — but might still protect against severe disease.

Double boost?a single booster with a different type of vaccinemight not be enough to subdue Omicron, warns Akiko Iwasaki, a viral immunologist at Yale School of Medicine in New Haven, Connecticut.Iwasaki and her co-authors studied blood samples from 101 individuals who received two doses of CoronaVac followed by an mRNA booster. Before the boost, the samples showed no detectable Omicron neutralization. Afterwards, 80% of analysed samples showed some Omicron-blocking activity

. But the quantities of antibodies that had Omicron-neutralizing potential were not much greater in this group than in a separate population that had received two doses of mRNA vaccine and no booster. The work has not yet been peer reviewed.Before the Omicron variant emerged, Iwasaki had been advocating single

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Covid hosted by HIV positive person equals omicron? Covid got a vaccine in than 2 years while HIV millions spent and years have gone, no vaccine. People will need to read the article to find out what you are really saying here. How many on Twitter will do so? How many will not but will now carry away some significant misinformation?

Please fix this tweet immediately. Hospitalization and Death are what matter here, not just infection. Learn how to communicate if you are going to tweet about an ongoing pandemic. They don’t mean the mRNA vaccines used in the US and Canada

COVID-19 live updates: New Zealand imposes restrictions amid omicron outbreakNew Zealand Prime Minister Jacinda Ardern revealed that her own wedding will be postponed as she announced a new set of COVID-19 restrictions amid the country’s first omicron outbreak. I feel just awful for those 30 or so folks who live in New Zealand. Thoughts and prayers, y'all. America is the shining beacon on the hill and JoeBiden is destroying it This is what happened when you give up guns!

FDA Curbs Use of COVID-19 Antibody Drugs Sidelined by OmicronU.S. health officials say COVID-19 antibody drugs from Regeneron and Eli Lilly should no longer be used because they are unlikely to work against the omicron variant. Did Delta disappear altogether?

Clinical Trials Begin For Pfizer And BioNTech’s Omicron-Specific Covid ShotI am a London-based reporter for Forbes covering breaking news. Previously, I have worked as a reporter for a specialist legal publication covering big data and as a freelance journalist and policy analyst covering science, tech and health. I have a master’s degree in Biological Natural Sciences and a master’s degree in the History and Philosophy of Science from the University of Cambridge. Follow me on Twitter theroberthart or email me at rhartforbes.com

Pfizer opens study of COVID shots updated to match omicronPfizer has begun a study comparing its original COVID-19 vaccine with doses specially tweaked to match the hugely contagious omicron variant. Pfizer...

Pfizer, BioNTech begin omicron-specific COVID-19 vaccine studyCOVID-19 vaccine-makers Pfizer and BioNTech announced Tuesday that the companies would test an omicron-specific vaccine candidate in healthy adults ages 18 to 55. Compare reporting from the right, left and center at Gtfo with your f vaccines! 🤮

Pfizer opens study of COVID shots updated to match omicronPfizer has begun a study comparing its original COVID-19 vaccine with doses specially tweaked to match the omicron variant.

have shown that a protein-based booster triggers higher numbers of neutralizing antibodies than does a third shot of an inactivated vaccine.Email this article New Zealand announced a new set of COVID-19 restrictions Sunday amid its first omicron outbreak.Boosters Effective Against Severe Illness From Omicron, CDC Studies Show Omicron’s resistance to the two leading monoclonal antibody medicines has upended the treatment playbook for COVID-19 in recent weeks.Share to Linkedin Topline Pfizer and BioNTech have begun a clinical trial for their omicron-specific coronavirus vaccine, the companies announced Tuesday, as vaccine makers scramble to reformulate shots to target the infectious variant.

Many of these results have not yet been peer reviewed. Double boost? a single booster with a different type of vaccine might not be enough to subdue Omicron, warns Akiko Iwasaki, a viral immunologist at Yale School of Medicine in New Haven, Connecticut. Prime Minister Jacinda Ardern reported in a press conference Sunday the variant is circulating in Auckland. Iwasaki and her co-authors studied blood samples from 101 individuals who received two doses of CoronaVac followed by an mRNA booster. The drugs are laboratory-made versions of virus-blocking antibodies. Before the boost, the samples showed no detectable Omicron neutralization. The family had just returned from attending a wedding and other events where there were more than 100 people, officials said. Afterwards, 80% of analysed samples showed some Omicron-blocking activity .  The companies said they do not expect manufacturing capacity—an estimated four billion doses in 2022—to change if they pivot to an omicron-specific shot.

But the quantities of antibodies that had Omicron-neutralizing potential were not much greater in this group than in a separate population that had received two doses of mRNA vaccine and no booster. -ABC News' Christine Theodorou Remdesivir approved for use in non-hospitalized patients Link Share to Twitter Email this article The Food and Drug Administration has expanded its approval for remdesivir, an antiviral drug used to treat COVID-19, to include people who are not hospitalized. The U. The work has not yet been peer reviewed. Before the Omicron variant emerged, Iwasaki had been advocating single mRNA boosters for recipients of inactivated vaccines. The expanded use was based on a study that found high-risk COVID-19 patients who were treated with remdesivir were less likely to be hospitalized than patients who got a placebo. “We were really celebrating how wonderful this strategy is,” she says, “and then — boom! — Omicron hit. But officials resumed distribution after complaints from Republican governors, including Florida’s Ron DeSantis, who claimed that the drugs continued to help some omicron patients.” Now, she thinks these people probably need two extra jabs. Patrizia Cavazzoni, director of the FDA’s Center for Drug Evaluation and Research, said in a statement Friday.

“The bar keeps being raised by the variants,” Iwasaki says. “We’re playing catch up all the time. -ABC News' Sasha Pezenik Biden has no authority to mandate vaccines for federal employees, judge rules Link Share to Twitter Email this article A federal judge in Texas shot down the Biden administration’s vaccine mandate for federal workers. Greg Abbott has also launched state-sponsored infusion sites.” Nature .