Novartis Cancer Drug Trial Doesn't Meet Primary Endpoints

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Novartis lung cancer drug doesn't meet primary endpoints in late trial

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By Cecilia Butini Novartis AG said Monday that a Phase 3 trial to evaluate a drug for use in lung cancer patients didn't meet its primary endpoints.

The Swiss pharma major said the trial, named CANOPY-1, didn't demonstrate statistical significance in overall survival and progression-free survival, meaning the time that a patient can live without the disease progressing. The trial evaluated canakinumab, a monoclonal antibody, in combination with chemotherapy for patients with non-small cell lung cancer.

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