Researchers studied 80 older women whose weight ranged from slightly overweight to severely obese, and split them into two groups for 16 weeks. Half the participants followed a medically supervised meal replacement plan with shakes that totaled about 800 calories per day. The other half was a control group that maintained their usual habits and weight for those months. Gut bacteria analysis was done for all participants before and after the study period.
After four months, the number and type of microorganisms in the control group were the same as they’d been at the start. But there were significant and problematic changes for the low-calorie diet group. For participants in the low-calorie group, the bacteria adapted to absorb more sugar molecules as a way to survive, creating an imbalance that promoted the increase of harmful bacterial strains. There was a particularly large increase in a type called Clostridioides difficile, also known as C. diff., which can cause diarrhea and colitis . TheThis effect from low-cal eating is not surprising.
, R.D., dietitian and nutritional counselor, the quantity of food we consume is part of what keeps beneficial gut bacteria nourished.plays such a large role in the composition and health of our gut microbiome,” she said.
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