Nitroglycerin: How An Explosive Became a Cardiac Drug

  • 📰 Medscape
  • ⏱ Reading Time:
  • 55 sec. here
  • 2 min. at publisher
  • 📊 Quality Score:
  • News: 25%
  • Publisher: 55%

United States Headlines News

United States Latest News,United States Headlines

Let's have a blast and review how this explosive became a cardiac drug. CardioTwitter TwitteRx theheartorg

Let's have a blast and review how this explosive became a cardiac drug.

Glyceryl trinitrate, or NTG, first entered the scene in the 1840s, when an Italian chemist, Ascanio Sobrero, created it by adding nitric acid and sulfuric acid to glycerol. The instability of this oily liquid is the reason it was often the weapon of choice for classic cartoon villains that you may remember fondly from childhood.

Although Sobrero would live until 1888, by which time the world of medicine was at least dabbling with NTG as a cardiac drug, the drug would not begin flourishing as a pharmaceutical until the early 1900s. This medical dabbling began with an action that Sobrero himself took prior discovering NTG's explosive property. He put a bit of it on his tongue, just to have a taste.

Keep in mind that this was the mid-19th century, when it was common for chemists to use their mouths as instruments the way that we might use a pH meter, or a photospectrometer. This was an era in which people sniffed nitrous oxide, ether, and chloroform for entertainment — leading to serendipitous medical discoveries — and that's what happened with NTG..

 

Thank you for your comment. Your comment will be published after being reviewed.
Please try again later.
We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

 /  🏆 386. in US

United States Latest News, United States Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Photos show underwater volcano’s explosive eruption in VanuatuReports of a volcano eruption in Vanuatu have locals in the area on high alert, with some sharing images of the eruption on social media.
Source: BGR - 🏆 234. / 63 Read more »

Undetonated explosive device discovered in New Cumberland: policeThe explosive device is believed to be from the World War II era.
Source: PennLive - 🏆 463. / 53 Read more »

How stars like Dolly Parton and Tom Hanks became American sweethearts | CNNAmerican sweethearts are the rare celebrities that most Americans can agree on due to their reputations of genuine kindness. Here's how some celebrities, like Dolly Parton, Tom Hanks and Oprah, endear themselves to the public and become cultural icons. 🤮🤮🤮🤮🤮🤮🤮🤮 🥱🥱
Source: CNN - 🏆 4. / 95 Read more »

How Sam Bankman-Fried’s Psychiatrist Became a Key Player at Crypto Exchange FTXSam Bankman-Fried’s psychiatrist became a key player at crypto exchange FTX before and after its failure Between WSJ and toilet paper, toilet paper wins, even after you've used it. Entitled trash.
Source: WSJ - 🏆 98. / 63 Read more »

Viola Davis Just Became An EGOT Winner“The Woman King” actor won her first Grammy for narrating her debut memoir, “Finding Me.” ABSOLUTELY! You can get a grammy for reading your own book?
Source: HuffPostWomen - 🏆 27. / 68 Read more »