The Pfizer study found that the vaccine appeared to work against 15 additional possible virus mutations, but E484K wasn’t among those tested. Dormitzer said it is next on the list.
Dr. Anthony Fauci, the top U.S. infectious disease expert, recently said vaccines are designed to recognize multiple parts of the spike protein, making it unlikely a single mutation could be enough to block them. But scientists around the world are conducting research with different vaccines to find out.
Dormitzer said if the virus eventually mutates enough that the vaccine needs adjusting — much like flu shots are adjusted most years — that tweaking the recipe wouldn’t be difficult for his company’s shot and similar ones. The vaccine is made with a piece of the virus genetic code, simple to switch, although it’s not clear what kind of additional testing regulators would require to make such a change.
Dormitzer said this was only the beginning “of ongoing monitoring of virus changes to see if any of them might impact on vaccine coverage.” Story by Lauren Neergaard of the Associated Press. The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
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