Multiple sclerosis drug to be studied for COVID-19 treatment

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The medication will be combined with remdesivir in ongoing clinical trials.

A large clinical trial, sponsored by the National Institutes of Health, will now study the effects of combining remdesivir with interferon beta-1a., suggested the interferon drug might help patients clear the virus more quickly.

"If we replace the interferon in conjunction with an antiviral [remdesivir], maybe we can prevent the progression of the disease," Kalil said."That's the hypothesis."About 1,000 patients hospitalized with COVID-19 worldwide will be included in the trial. Half will receive remdesivir plus shots of interferon beta-1a, four times every other day. The other half will get remdesivir plus placebo shots.

Kalil's team is also wrapping up studies of remdesivir plus an anotther drug, an anti-inflammatory calledBaricitinib, manufactured by Eli Lilly and marketed as Olumiant, is what's known as a Janus kinase inhibitor. It blocks an enzyme that helps produce chemicals that lead to inflammation.

 

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