Largest COVID-19 study outside China: symptom 'clusters,' obesity risk - Business Insider

The study identified four major risk factors that can make a person more susceptible to severe illness or death from COVID-19: age, male sex, obesity, and underlying conditions affecting the heart, lungs, kidney, or liver.

Previous studies of this scale have not highlighted obesity as a risk factor. The hospitalized patients' median age was 73, and 60% of them were male.Less than half of the patients had left the hospital alive by May 3, when the researchers wrote the study. They were all hospitalized between February 6 and April 19.A cyclist has her temperature checked at the entrance of Idroscalo artificial lake, as Italy eases some of its lockdown measures, in Milan, Italy, May 23, 2020.

That includes musculoskeletal symptoms like muscle aches, joint pain, headache, and fatigue. Gastrointestinal symptoms, which appeared in 29% of patients upon their admission to the hospital, include abdominal pain, vomiting, and diarrhea. A less common "Though cough, fever, and shortness of breath — the respiratory cluster — remained the most common symptoms, they each only appeared in roughly 70% of patients. Some patients had no respiratory symptoms at all.

Patient Doreen Mount is comforted by a Radiologist in the X-ray department at The Royal Blackburn Teaching Hospital in East Lancashire, following the outbreak of the coronavirus disease , in Blackburn, Britain, May 14, 2020."The current case definition of cough and fever, if strictly applied, would miss 7% of our inpatients," the study authors wrote.

About 4% of the patients had only gastrointestinal symptoms, though the authors noted that "this figure could be an underestimate because these patients fall outside standard criteria for testing.". The researchers expect to release more results in the future.

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