. The decision was based on evidence suggesting that spacing out the doses may improve effectiveness in some cases.
Others say, however, that there’s not enough data to support this approach, and it has a major downside: People aren’t fully protected during the three month interval between shots. “We have to stick with what we know works,” Nancy Messonnier, the director of the Centers for Disease Control and Prevention’s National Center for Immunization and Respiratory Diseases,. “This is the regimen that’s been carefully studied.
As such, Dr. Malani emphasizes that it’s best to shoot for the CDC recommended interval between doses, or as close to it as possible. Even outside of the 42-day grace period, though, Dr. Malani says that there’s still a benefit to getting the second dose; just schedule it as soon as you can.
The second shot is critical for the mRNA vaccines because it acts as a booster. While studies have indicated that the Pfizer and Moderna vaccines are between
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