Is a universal coronavirus vaccine on the horizon?

“It’s pretty clear that the virus continues to evolve and going forward there is a need for a universal COVID-19 vaccine or even a universal coronavirus vaccine.”

Omicron, Delta

1/19/2022 5:39:00 PM

“It’s pretty clear that the virus continues to evolve and going forward there is a need for a universal COVID-19 vaccine or even a universal coronavirus vaccine.”

Scientists are racing to develop a single vaccine that protects against many SARS-CoV-2 variants, as well as emerging coronaviruses with the potential to trigger a new pandemic.

the vaccine’s ability to generate antibodies that neutralize and block the entry of SARS-CoV and SARS-CoV-2 and its major variants (excluding Omicron, which was not tested) into animal cells. “The repetitive and ordered display of the coronavirus spike protein on a multi-faceted nanoparticle may stimulate immunity in such a way as to translate into significantly broader protection,” Kayvon Modjarrad, co-inventor of the vaccine, stated in a

. His team is currently analyzing the Phase I data.National Geographicreached out to Walter Reed multiple times for more details, but they declined to comment until the results of the Phase I trials are published.Other universal coronavirus vaccine efforts involve targeting a slow evolving, genetic and structurally similar region on the viruses—where antibodies bind as part of a body’s immune response to a foreign invader—or additionally engaging the body’s immune cells called T cells.

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No need for a universal coronavirus vaccine as most coronavirusses will just cause a disease know as the common cold. For God's sake give it up already 🤪 Most idiotic shit ever. Its called the flu shot. You can stick your mrna mandates up your $$ Yeah, just add it to list of vaccines needed to attend school.

Better sink those billions in profits into a real vaccine then...cause I'm one and done. I am not lining up every six months for a booster. More money to scam the world! Nice one producing those variant! Educate yourself for God’s sake! Of course, the effort must continue and we must accept that to date there have been No 100% effective vaccinations for any strain of flu virus. It also should be considered that each new vax informs viruses on how to mutate. When humans declare war on nature - humans lose.

Need to vaccinate our cows and pigs and any other meat ppl consume... That's where it starts. Vet scientists are going in caves to vaccinate bats for certain diseases and chickens, Imagine we could do this for all farm animals possible.

Covid-19 news: Joint flu and covid-19 vaccine could be offered in 2023Today’s covid-19 news: · Single covid-19 and flu vaccine could be available in 2023, says Moderna CEO · England coronavirus restrictions might end in March · Thousands of hamsters euthanised in Hong Kong following evidence of coronavirus transmission imagine getting vaxxed when u can just get ripped Hi, I am a structural engineer from Iran who have many ideas. I have summarized some of my ideas on my twitter(I suggest look at the idea of generating electricity by gravity). I want to work with companies and investors. Do you want to cooperate? If near Qiyamah you see the real Islam spreading from the land before Khurasan, then join even if you have to crawl with naked feet over the mountains to get there. A blessed dream of Muhammad Qasim. I think he is the Imam Al-Mahdi.

Cannabis may do the trick but the Big Pharma can not patent it so bribed politicans keep cure illegal. Created in lab for profit, follow the money. There's more a need for ones choice to do with their own body to remain ... if that is lost then freedom is more of a farce then it is at present! Don’t humans evolve also?

Nope !!! Perronne KKMPutrajaya Khairykj anda faham realiti tetapi anda sombong dan hanya gila akan kuasa dan jawatan. Anda begitu munafik dan tidak mencermin kebijaksaan malah hanya kaki tiru sana-sini. Adalah manusia sama kerana anda yg banyak bercakap. Apa yg anda tahu tentang badan manusia. So, end colds forever?

It can stay on the horizon and not in my body 落叶归涴。 COVIDdata

Covid-19 news: Most short-term vaccine symptoms down to nocebo effectToday’s covid-19 news: · Most short-term vaccine symptoms may be caused by nocebo effect · UK reports highest daily death toll since February 2021 · Spain considers treating covid-19 as “endemic” illness like flu Shout out to Spain keeping it real… long overdue Hey everyone, if you like history then please check out my new video about ice age animals, I also have other videos such as the origins of ancient Egypt. Any feedback or support would be greatly appreciated, thanks! The nocebo effect seems to be an obvious consequence of communicating malaise to each other due to a genuine reaction and anti-vaccine propaganda.

That will not please the hard of thinking. Every fall we will go and get stabbed for influenza & covid. What about AIDS vaccine? That would be really needed too... but kako pangalanan needs fertilizers for its farm. Let’s take it further and have a universal vaccine for all the viruses & one for all the bad bacterias…it is possible?, just need to think out of the box…and one antidote for all the poisons in the world…can someone fulfil my 3 wishes? easier way is to make your immunity talk!

'Evolve'? Sure.... Not even close… too much cash still to drain from everyone with the booster doses… I’m grateful that they got a vaccine quickly with mRNA, but we really do need something more like a flu vaccine that we only need once a year. Uhh...... NO ! 😳

Illinois Coronavirus Updates: Test Kit Website, Free N95 Masks, Pritzker to SpeakHere’s what you need to know about the coronavirus pandemic across Illinois today. Anyone going to ask the question about how distributing N95 and not following the OSHA respirator standard is going to work? OSHA can fine employers for not implementing a full blown policy.

This is the most absurd statement regarding A spike protein exterior virus (& or certain parasites also). Spike protein cell changes it shapes to fool bodies defense of previous used shape cuts a key. You must be promoting extinction.Human brain 10% use restricted & Proud of it? Great but don't need it lol.

Lies are expensive.. Is a universal flu shot on the horizon? That's a no to both. Is Coronavirus no longer a spike protein exterior cell virus? This would be from genetic manipulation only which would be bioterrorism a vaccine with a spike protein promotes mutations if selling products is the goal and killing people genocide you have the right idea

Omg! Been fighting the cold and flu since 1933 and to this day people still get the flu . So I don't expect covid to be any different ¿How long will take to get a universal coronavirus vaccine? 5 - 10 years? A mess

NJ Fund For Immigrants Distributed A Fraction Of Aid, Reallocated $34M For State BudgetWNYC/Gothamist has confirmed most of New Jersey’s $40 million fund to help immigrants and other residents excluded from COVID-related aid during the pandemic will be re-allocated to other state expenses such as payroll. “It's just a slap in the face.' well that's fucking awful. CasaFreehold domesticworkers NDLON GovMurphy LtGovOliver Shame on you Governor Murphy!!! NJ has the 3rd largest immigrant population in the U.S. You are breaking your promise to NJ’s essential workers! Keep your promise! 1Billion

Need to stop relying on vaccines and continue to develop better anti-retroviral drugs. The spike protein is going to continuously change, the internal machinery of the virus isn't going to significantly. Kinda like the flu shot? People that are fully vaccinated w BOTH doses, AND the booster ARE DYING FROM THE VIRUS. OBVIOUSLY, THE VACCINE DOES NOT WORK! Why are you still pushing vaccines? Do you have a steak in the companies that are producing the vaccines? How much did they PAY YOU for advertising them?

Yeah, look at Isreal, one of the leading vaccinated countries We already have one. It’s called the “seasonal flu shot” Never needed a vaccine for a bad cold before, not sure why you think we need one now. Redundant? It does just that, evolves as all things do. Humans will be behind it, as nature was here first. There are at least 144 substrates of influenza. In years time, most likely will be a Covid-55 megatron omnicron. And by then there will be more pressing matters than this virus.

It’s pretty clear that the vaccines don’t work and this was never about health or even about saving lives

Covid: Cummings claims PM was warned about lockdown drinks, and job vacancies hit new highFive things you need to know about the coronavirus pandemic this Tuesday morning. Yes..like some monitoring enhanced..but terrible of No Home device to Monitor Important Balance and Elements to Body Input/ Output.. and they can find other floors to play on--

True ,also Some universal prayer worldwide can also do wonders as well on top of a cure Please, kill me already. You just lost my respect and my follow. What you are posting is pure bullship. Never thought of National Geographic as a goat but this is proof. Now do the story on how in Europe we're seeing negative efficacy of the vaccinated against Omicron.

Beijing Olympics tickets will only be available to 'spectators from selected groups,' organizers sayThe Olympics will have strict guidelines to prevent the spread of the coronavirus. Lol. CCP giving out red notice if you break rules

showed the vaccine’s ability to generate antibodies that neutralize and block the entry of SARS-CoV and SARS-CoV-2 and its major variants (excluding Omicron, which was not tested) into animal cells. “The repetitive and ordered display of the coronavirus spike protein on a multi-faceted nanoparticle may stimulate immunity in such a way as to translate into significantly broader protection,” Kayvon Modjarrad, co-inventor of the vaccine, stated in a . His team is currently analyzing the Phase I data. National Geographic reached out to Walter Reed multiple times for more details, but they declined to comment until the results of the Phase I trials are published. Other universal coronavirus vaccine efforts involve targeting a slow evolving, genetic and structurally similar region on the viruses—where antibodies bind as part of a body’s immune response to a foreign invader—or additionally engaging the body’s immune cells called T cells. Zeichner, for instance, is focusing on the fusion peptide region, which is part of the coronavirus spike protein that aids the entry of the virus into host cells, to develop a pan-coronavirus vaccine. “It is extremely conserved among all coronaviruses,” he says. “It doesn’t mutate very much.” Along with colleagues, he tested a proof-of-concept vaccine using a SARS-CoV-2 fusion peptide and early results indicated that in pigs the vaccine provided some protection against a different coronavirus , called porcine epidemic diarrhea virus, that doesn’t infect humans. His team is now collaborating with researchers at Virginia Tech and the International Vaccine Institute in Seoul to further develop and continue testing the vaccine against different SARS-CoV-2 variants and other coronaviruses. Björkman and her colleagues, on the other hand, are focusing on a more specific target: the spike protein’s receptor-binding domain (RBD). It’s the region of the spike to which most antibodies bind to prevent SARS-CoV-2 from entering the host cell; it is also the region within which mutations occur, giving rise to variants. For the vaccine, they used RBD proteins from up to eight viruses—including the original SARS-CoV-2 and other SARS-like coronaviruses isolated from bats—that were fused onto a nanoparticle with 60 faces. By injecting this vaccine into mice, Björkman and her colleagues found the animals produced diverse antibodies, which in follow-up experiments blocked infections caused by several SARS-like viruses, including coronavirus strains not used to create the vaccines. To Björkman, this suggests that the animal’s immune system might be learning to recognize common features between the coronaviruses and that her mosaic vaccine, with pieces selected from multiple viruses, might be useful when new SARS-like viruses or new SARS-CoV-2 variants emerge. Her team is currently gearing up to test the vaccine in humans. Vaccine researcher Kevin Saunders at the Duke Human Vaccine Institute is also focusing on the RBD, but a very specific part of it, to make a pan-SARS-like virus vaccine. When the pandemic began in early 2020, Saunders and his colleagues began hunting for antibodies that would inactivate SARS-like viruses. They examined antibodies present in frozen stored cells of an individual who recovered from SARS-CoV infection and another individual previously infected with COVID-19. They identified a potent antibody dubbed DH1047 occurring in cells from both patients that could block infections in which mice that had been injected with  several bat and human coronaviruses, including SARS-CoV-2 variants. A closer look revealed the antibody bound to the same small section of the spike protein’s RBD in different coronaviruses, which became the vaccine target. By injecting monkeys with multiple copies of this SARS-CoV-2 RBD piece fused to a nanoparticle, Saunders and his colleagues demonstrated the vaccine’s ability to protect against not just SARS-CoV-2 but several other coronavirus infections. The team is now testing different iterations of this nanoparticle vaccine by introducing RDB sections from other coronaviruses to broaden the host’s immune response. “Sometimes you make hundreds of versions of these [vaccines] and test them in animals before deciding on a version to study in humans,” says Julie Ledgerwood, deputy director and chief medical officer at the National Institutes of Health’s Vaccine Research Center. It’s not simple, she says. Meanwhile, scientists are also trying to figure out how these vaccines could cover not just SARS-like viruses but MERS and other more distantly-related coronaviruses too. “The sequence diversity and structural differences between coronaviruses that fall into different groups is going to be a challenge,” Saunders says. Some scientists propose a different vaccine for different coronavirus families. For now, though, the need for at least a pan-SARS-like coronavirus vaccine cannot be ignored. “We’re no longer thinking of this as ‘it’ll be great to have this for the next pandemic,’” Saunders says. “We’re thinking of this as a great tool to stop this pandemic.” Share