I got the Moderna vaccine. Can I get a Pfizer booster?

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Pfizer booster shots are authorized for certain adults, but what about people who got Moderna or J&J? Here's what to know about mixing and matching vaccine.

“There’s very limited data on mixing and matching vaccine types and essentially no data on mixing and matching delayed booster vaccines,” she said.is studying how people respond to receiving a booster shot that’s a different vaccine than their initial full dose. The trial is currently in the first of two phases.

That’s because the two vaccines use different technologies to trigger immunity. The Johnson & Johnson vaccine does not use mRNA but rather uses a weakened version of what’s called an adenovirus. This virus can’t make a person sick; instead, it’s modified to enter the body and teach the immune system how to protect itself against the coronavirus. AstraZeneca’s vaccine works in the same manner.

According to Dr. Steven Carsons, director of the Vaccine Center at NYU Langone Hospital—Long Island, receiving both an adenovirus vaccine and an mRNA vaccine may provide different pieces of information to the immune system’s memory, potentially better equipping it to quickly recognize and fight off the coronavirus. The same could be true for the two mRNA vaccines, which each use slightly different proteins to train the immune system.Dr.

 

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