The Food and Drug Administration is expected to say this week that people can get coronavirus vaccine booster shots that are different from their initial doses, according to two people familiar with the situation.The agency is rushing to make the announcement Wednesday as part of its authorization of boosters for Moderna and Johnson & Johnson vaccines.
Johnson & Johnson has been shown to be less effective than the Pfizer-BioNTech and Moderna vaccines so there is intense focus on how to boost the single-shot Johnson & Johnson recipients: Should it be with the Johnson & Johnson shot or with the other vaccines, which use a different technology?A key matter of debate: If Moderna is used as a booster for Johnson & Johnson, what should be the correct dose? Some officials say it should be a half-dose of the regular shot — the dosage...
“People should generally get the same vaccine as their initial series,” said one of the federal officials familiar with the situation. But the official said people in nursing homes might not have access to their original vaccine, or that some people might have had a bad reaction to the mRNA vaccines, the technology used to make the Pfizer-BioNTech and Moderna shots.
Documents from the FDA provided to committee members included an agency review of Johnson & Johnson’s tests of a second dose of its own vaccine and a separatethat tested mixing booster doses from different companies. The data could provide a road map for the 15 million people who received the Johnson & Johnson vaccine in the United States, many of whom have felt left out because the vast majority of U.S. vaccine recipients received vaccines from Pfizer-BioNTech or Moderna.
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