Explainer: What J&J's authorized COVID-19 shot means for the U.S. vaccination campaign

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Johnson & Johnson's one-shot COVID-19 vaccine received U.S. authorization on Saturday and will start being administered to Americans within days.

NEW YORK - Johnson & Johnson’s one-shot COVID-19 vaccine received U.S. authorization on Saturday and will start being administered to Americans within days.

However, the trials had important differences, making comparison difficult. Pfizer and Moderna focused on efficacy against mild-to-moderate sickness, while J&J’s trial looked for efficacy against moderate-to-severe COVID-19. All three vaccines have a similar range of short-lived side effects, including fatigue, aches, injection site soreness, nausea and fever, mostly mild-to-moderate.J&J’s vaccine is a single shot. Pfizer/BioNTech and Moderna vaccines each require two shots three or four weeks apart.

J&J’s vaccine is one of the few that has been tested in clinical trails against the worrisome virus variant first discovered in South Africa. It demonstrated an ability to provide protection against severe disease and death even for those infected with that variant. Pfizer and Moderna have only tested their vaccines against the variant in the lab and believe they will remain protective.

 

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RT : Explainer: What J&J's authorized COVID-19 shot means for the U.S. vaccination campaign

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