Early treatment could help ease peanut allergies in young kids, study says

Young children might be able to overcome their peanut allergies if treated at an early enough age, according to a study published Thursday.

News

1/21/2022 6:32:00 AM

Young children might be able to overcome their peanut allergies if treated at an early enough age, according to a study published in the journal Lancet.

Young children might be able to overcome their peanut allergies if treated at an early enough age, according to a study published Thursday.

The approach seemed to work best in the youngest children and those with milder allergies, the researchers reported Thursday in the journal Lancet.The findings suggest there’s “a window of opportunity” early in life when treatment could have a lasting impact, said Dr. Stacie Jones, a study co-author from the University of Arkansas for Medical Services. But she said more research is needed to determine how long the effect might continue.

A treatment for peanut allergies already exists but it is only approved for ages 4 and older, and the protection it provides is for the accidental exposure to small amounts of peanuts. Children are still supposed to avoid eating the nuts, and carry an EpiPen or other medicine for allergic reactions. It also uses peanut powder, but when children stop taking the treatment, the protection stops.

Read more: NBC News »

'I played dead': Boy who survived TX school shooting recalls gunman saying 'you're all gonna die'

'I played dead so he wouldn't shoot me,' 10-year-old Samuel Salinas told ABC News. Read more >>

‘When We Were Young' Festival Will Bring Best of Early 2000s Emo-Pop to Las Vegas'When We Were Young': No more misery business -- a new music festival is bringing a whole host of popular emo-pop bands from the early 2000s to Las Vegas for one night in October 2022. I know we all have our tastes in music. For me, this is about as appetizing as a pickle peanut butter Oreo smoothie🤮 Yeah… No thanks.. Warped tour was what, $40? And each band did at most 4 songs.. Not worth it for one night at that price.. ThePerezHilton

Valneva Shares Jump After Early Study Show Covid-19 Vaccine Effective Against OmicronI am a London-based reporter for Forbes covering breaking news. Previously, I have worked as a reporter for a specialist legal publication covering big data and as a freelance journalist and policy analyst covering science, tech and health. I have a master’s degree in Biological Natural Sciences and a master’s degree in the History and Philosophy of Science from the University of Cambridge. Follow me on Twitter theroberthart or email me at rhartforbes.com

Something in Your Eyes May Reveal if You're at Risk of Early Death, Study ShowsA quick and pain-free scan of the human eyeball could one day help doctors identify 'fast agers', who are at greater risk of early mortality. Hi, I am a structural engineer from Iran who have many ideas. I have summarized some of my ideas on my twitter(I suggest look at the idea of generating electricity by gravity). I want to work with companies and investors. Do you want to cooperate?

I Am Groot Early Release Date Hopes Created By Marvel 2022 Toy WaveHot Toys' announcement of this year's Marvel collectible releases is seemingly pointing towards an upcoming release date announcement for IAmGroot.

Drivers warm up buses, some schools open early due to arctic blastMany North Texas school districts took extra steps Thursday morning to keep kids out of the bitter cold. One vaccine site in Dallas County is also opening late because of the weather. Same weather as about 35 other states will have daily for the next 2 months, but sure....

Report: Meta and Instagram Are Exploring an 'Early Stage' NFT Feature – Bitcoin NewsMeta Platforms, Inc., formerly known as Facebook, Inc., is reportedly experimenting with non-fungible token (NFT) technology. Best strategy I ever took was buying a little bit every day and increasing the amount of those buys during dips into bitcoin is the best strategy of the past decade Following Bernie_doran01 tweets, prediction and tips I have really learnt a lot about how Bitcoin works BabyDogeCoin Meta Master will be one of the biggest crypto projects of 2022! Do not miss it, the first cross chain, cross currency Metaverse! 💎 🚀 Join the Telegram for more info blockchain cryptocurrency crypto Cryptos BSC

The researchers gave increasing amounts of peanut protein powder to a group of toddlers to build up their tolerance for peanuts. After 2 1/2 years, close to three-quarters could tolerate the equivalent of 16 peanuts without an allergic reaction. Six months after treatment stopped, one-fifth still had the same tolerance. The approach seemed to work best in the youngest children and those with milder allergies, the researchers reported Thursday in the journal Lancet. The findings suggest there’s “a window of opportunity” early in life when treatment could have a lasting impact, said Dr. Stacie Jones, a study co-author from the University of Arkansas for Medical Services. But she said more research is needed to determine how long the effect might continue. A treatment for peanut allergies already exists but it is only approved for ages 4 and older, and the protection it provides is for the accidental exposure to small amounts of peanuts. Children are still supposed to avoid eating the nuts, and carry an EpiPen or other medicine for allergic reactions. It also uses peanut powder, but when children stop taking the treatment, the protection stops. Jones and her colleagues tested a similar approach on younger children to see if their immune systems could be changed if treated at an earlier age. She helped lead a study for the current treatment, Aimmune Therapeutics’ Palforzia, and has consulted for the company. About 2 percent of children in the U.S. have peanut allergies, which can cause severe reactions and be a source of constant worry for parents. Some children outgrow the allergy, but most have to continue avoiding peanuts for life. To prevent the allergies from developing, health experts in recent years have encouraged parents to feed babies with peanut-containing foods early on. Feb. 3, 2020 00:29 The new government-funded study involved 146 children in the U.S. ages 1 to 3. They were given daily doses of peanut powder mixed in food or a dummy powder — oat flour. When the treatment ended, 71 percent of those who got the peanut powder could tolerate the equivalent of 16 peanuts. Six months later, 21 percent still could. In the dummy powder comparison group, 2 percent could tolerate 16 peanuts at the end of the treatment and six months later. Most of the children had a reaction during treatment, mostly mild to moderate. Some in the peanut group required treatment with an EpiPen. The research “really supports something that we thought for a while in the field,” said Dr. Joyce Hsu, an allergy specialist at Brigham and Women’s Hospital in Boston who was not involved in the study. “Children’s immune systems are generally more malleable when they are younger.” Hsu’s clinic offers an allergy treatment with peanut protein for children ages 4 months and older. As with Palforzia, Hsu noted it is intended to protect against accidental ingestion, and that children are still supposed to avoid peanuts. She said there has been a lack of strong data about treating peanut allergies in infants and very young children. In a commentary published with the study, other allergy experts noted the wide availability of the peanut powder used in the study. They said the treatment is a reasonable option that’s ready for real-world implementation, under the guidance of an allergy specialist. Dr. John Kelso, an allergy specialist at Scripps Clinic in San Diego, said the findings should give doctors more confidence to try the treatment for toddlers, and offer it to parents. But he noted that it’s still not clear whether any tolerance would have a limit or how it might change over time. “There still needs to be some caution about thinking of this as a cure,” he said.