Could this plant extract help fight the opioid epidemic?

As the opioid epidemic continues to claim lives, UC Irvine researchers have identified a plant extract that may help fight opiate addiction.

The COVID-19 pandemic has further worsened the opioid crisis, with more people dying of overdoses. The number of opioid overdose deaths has more than doubled in Orange County over the last decade. According to the Orange County Health Care Agency, 234 residents died of opioid overdoses in 2011, compared with 499 in 2020. A huge contributor to the number of opioid deaths is the powerful synthetic drug fentanyl, which accounted for 381 of the deaths last year. The Orange County coroner did not test for fentanyl or other synthetic opioid types in 2010, said Dr. Curtis Condon, research manager at the agency.

“When people take an opioid, especially morphine, but all the opioids like oxycodone and others that are on the market these days, people lose the effectiveness of the opiate … they need to take more and more and more,” Civelli said. “That is drastic because that is what leads people to take more and more and risk overdose.”

Civelli said researchers are now trying to determine how the extract blocks morphine tolerance. He is also hoping that further research will be done on how the drug acts when ingested by humans.More than 93,000 people

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