Coronavirus Variants Are Posing New Threats To Vaccines

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On Monday, Moderna announced its COVID-19 vaccine is still protective, but slightly less potent, against a new coronavirus mutant.

“Many people’s guess is it’s much higher than [what has been reported], and we’ll be looking for it on a much more continuous basis,” Mark Ghaly, California’s secretary of health and human services, said in a press briefing.

“It may be that we will have to change the vaccine so that it is more responsive to new variants,” said Kathryn Edwards, scientific director of the Vanderbilt Vaccine Research Program, speaking at a recent Infectious Diseases Society of America briefing. “But at this point it doesn't seem that that's the case.”Sara Saravia, 81, receives a vaccine shot in Los Angeles on Jan. 23.

“Certainly the data from South Africa is concerning, and I definitely expect the virus to evolve to evade our immune system even if this set of variants do not,” Russ Corbett-Detig, a biomolecular engineer at the University of California, Santa Cruz, said by email. “If these new variants are able to escape the immune response, that's bad news.”

“The only way we will know if a variant is a problem for vaccines is if we see significant numbers of people who have been vaccinated being admitted to the hospital,” Paul Offit, a vaccine expert at the Children’s Hospital of Philadelphia, told BuzzFeed News. “That is the only proof, and it will take time. Everything else until then is just someone trying to make a prediction.”

 

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