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CanSinoBIO's COVID vaccine, tested at lower dosage, safe for children -study

CanSinoBIO's COVID vaccine, tested at lower dosage, safe for children -study

9/26/2021 6:35:00 PM

CanSinoBIO's COVID vaccine, tested at lower dosage, safe for children -study

CanSino Biologics Inc's (CanSinoBIO) , single-dose COVID -19 vaccine, given at a lower dosage than that for adults, is safe and triggers an immune response in children aged 6-17, results from a small trial showed.

2 minute readA logo of China's vaccine specialist CanSino Biologics Inc is pictured on the company's headquarters in Tianjin, following an outbreak of the coronavirus disease (COVID-19), China August 17, 2020. REUTERS/Thomas PeterBEIJING, Sept 24 (Reuters) - CanSino Biologics Inc's (CanSinoBIO)

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(6185.HK), single-dose COVID-19 vaccine, given at a lower dosage than that for adults, is safe and triggers an immune response in children aged 6-17, results from a small trial showed.Researchers decided to lower the dosage after a few participants developed fever and headaches graded at level 2 severity - the second-lowest of four levels. In children, the lower dose triggered higher antibody levels than the dosage approved for use in adults in China, according to the peer-reviewed

from a mid-stage trial.The trial recruited 150 children and around 300 adults.The results also showed that children given one lower dose had a stronger antibody response than adults who were given a booster shot 56 days after the first dose.But the antibody readings did not show to what extent the vaccine can offer protection against COVID-19, researchers from a Chinese disease control agency, CanSinoBIO and other Chinese institutes cautioned in a paper. headtopics.com

CanSinoBIO's vaccine has not yet got the greenlight for children. China has approved three COVID-19 vaccines for use in children from the age of three: its two most commonly used shots from Sinovac(SVA.O)and Sinopharm plus a third shot from Sinopharm. Vaccinations have yet to begin for those under 12.

The paper said the booster shot for CanSinoBIO's vaccine improved antibody responses in participants of different age groups, especially for older adults.But cellular responses, another important part of human immune system, were not boosted by the second shot and researchers said a wider interval than 56 days should be considered.

Reporting by Roxanne Liu and Ryan Woo; Editing by Edwina GibbsOur Standards:More from ReutersSign up for our newsletterSubscribe for our daily curated newsletter to receive the latest exclusive Reuters coverage delivered to your inbox. Read more: Reuters Top News »

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