Bizarre knotted DNA structures linked to cancer in mice

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Missing enzymes may cause troublesome knots to appear in DNA.

Oddly tangled and looped DNA structures could be linked to cancer, according to a new study in mice. DNA typically looks like a twisted ladder.

But the loss of key enzymes in the body causes the genetic molecule to become tangled up in bizarre loops and knots, and at least in mice, these odd DNA structures may drive the development of cancer, The Scientist reported . Specifically, a family of enzymes known as ten-eleven translocation enzymes seems critical to preventing DNA from…

 

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The loss of key enzymes in the body causes the genetic molecule to become tangled is caused by internal gas. Most diseases are caused by gas. DNA

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