Antibody drug may cut Covid-19 hospitalizations, company says.
Eli Lilly released partial results from a study on its monoclonal antibody drug.
They are being tested to treat newly diagnosed Covid-19 patients in hope of preventing serious disease or death, and to try to prevent infection in people at high risk of that such as nursing home residents and health workers.Wednesday’s results come from 450 people in a mid-stage study testing an antibody jointly developed by Indianapolis-based Lilly and the Canadian company AbCellera in people with Covid-19 symptoms not severe enough to warrant hospitalization. The drug is given once through an IV and was tested at three doses. Neither the patients nor their doctors knew which patients received the drug or placebo infusions.
Download theNBC News appfor full coverage of the coronavirus outbreakHospitalization or ER visits occurred in 1.7 percent, or 5 of 302 patients given the drug and 6 percent or 9 of 150 of those given placebo. The company did not disclose whether those results met scientific tests to rule out that they could have occurred by chance alone.
The company felt that giving the actual numbers"told the story in the most balanced way,” said Lilly’s chief scientific officer, Dr. Daniel Skovronsky.The difference seems large enough to suggest a true benefit and the result is “promising” even though the study missed its main goal, said Dr. Peter Bach, a health policy expert at Memorial Sloan Kettering Cancer Center in New York with no role in the study.
The study will continue to test the antibody drug in combination with another from a Chinese company, Junshi Biosciences.Three late-stage studies of italso are underway, including two sponsored by the U.S. National Institutes of Health.Lilly has already started manufacturing its antibody drug, hoping to have hundreds of thousands of doses ready by fall if studies give positive results.
Another company that developed an antibody drug cocktail against Ebola — Regeneron Pharmaceuticals Inc. — now is testing a two-antibody drug for coronavirus. Read more: NBC News »
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Incredible. There's various nano antibody efforts and the best really deserve support/coverage Saying is easy doing is hard and can be confirmed in a transparent society
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