3D printing makes it easier to create tissue for medical research

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Cultivating cells in a Petri dish is a time-honoured way of experimenting on biological tissues. But it is not particularly reliable

in a Petri dish is a time-honoured way of experimenting on biological tissues. But it is not particularly reliable. The problem is that cells often need specific structural support to function correctly. To provide this, tissue engineers are turning toprinters to make tiny bespoke scaffolds onto which cells are “seeded”. This encourages those cells to grow and develop. As research into tissue engineering advances, so too do ways of printing the scaffolds.

Glioblastoma is an aggressive cancer that begins in the brain, and rapidly evolves resistance to drugs. The best chance of treatment is to cultivate, in the laboratory, samples of an individual’s tumour and then bombard these with different combinations of drugs until an effective mixture is found.

In the second example, Filippos Tourlomousis of the Massachusetts Institute of Technology, working with a team at the Stevens Institute of Technology, in New Jersey, produced a scaffold from polymer fibres a mere hundredth of a millimetre wide—far smaller than mostprinters can manage. The team did this by drawing the fibres out using an electric field applied between the print nozzle and the surface onto which the fibres were being printed.

 

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