By Dr. Priyom Bose, Ph.D.Sep 20 2022Reviewed by Danielle Ellis, B.Sc. The ongoing coronavirus disease 2019 pandemic, caused by the rapid outbreak of severe acute respiratory syndrome coronavirus-2 , has claimed more than 6.52 million lives worldwide. The emergence of SARS-CoV-2 variants due to genomic mutations has prolonged the pandemic. Some SARS-CoV-2 variants, such as the Omicron and Delta, are more transmissible and virulent than the ancestral strain.
A recent JAMA Network Open study assessed the dynamic trajectory of COVID-19 symptom burden as well as symptom persistence in those who survived SARS-CoV-2 infection for two years after being discharged from hospitals. Apart from the telephonic interview, all participants also provided a self-reported symptom questionnaire along with a chronic obstructive pulmonary disease assessment test . The symptoms of the participants were recorded as no problems, mild problems, moderate problems, or severe problems. Patients having at least one persistent COVID-19 symptom represented long COVID.
In this study, a higher risk of symptom persistence was linked with ICU admission. Additionally, COVID-19 infection in patients with cerebrovascular diseases was associated with the manifestation of the onset of new symptoms. 6.2% of participants exhibited CAT scores of at least 10. The current study observed a higher risk of symptom persistence in recovered COVID-19 patients who needed ICU care during their hospital stay or had chronic liver diseases.
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