Traumatic Brain Injury Associates with an Earlier Onset in Sporadic Frontotemporal Dementia - IOS Press

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Educationalbackground and previous brain injury may be associated with higher risk of frontotemporaldementia IOSPress_STM

[*] Correspondence to: Eino Solje, MD, PhD, Adjunct Professor, Research Director, University of Eastern Finland – Institute of clinical medicine, Neurology, P.O. Box 1627 FI-70211 Kuopio, Finland. Tel.: +358 408425553; E-mail:Background:Currently, there are few studies considering possible modifiable risk factors of frontotemporal dementia .

phenotype or onset age in FTD patients. Methods:We compared the prevalence of prior TBI between individuals with FTD and age and sex-matched AD patients or healthy controls . Based on the patient records, an individual was categorized to the TBI+ group if they were reported to have suffered from TBI during lifetime. The possible associations of TBI with age of onset and disease duration were also evaluated in the whole FTD patient group or separately in the sporadic and genetic FTD groups.

 

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