Study highlights optimal timing for assessing orthostatic hypotension in older adults and its impact on fall risk

Change in SBP (A), DBP (B), and HR (C), over 6 measurements after standing from supine position. Horizontal axis represents average time after standing for respective measurements (e.g., M1=0m 44s). Leftmost dashed line indicates transition from supine to standing. Rightmost dashed line indicates cutoff between early and late BP and HR measurements (i.e., 3 minutes after standing). NA=NB=491 participants. NC=488 participants.

Key findings from the study, which involved community-dwelling adults aged 70 and older, revealed that orthostatic hypotension was most prevalent and symptomatic within 1-2 minutes after standing. However, the study also demonstrated that orthostatic hypotension assessments conducted after 4 to 6 minutes of standing were more informative for predicting fall risk.

According to Lewis A. Lipsitz, MD, Director, Hebrew SeniorLife Marcus Institute for Aging Research and Hebrew SeniorLife's Chief Academic Officer,"The findings have important implications because falls represent a major cause of serious, life-threatening injury in, and understanding the timing of orthostatic hypotension assessments can help clinicians identify those at highest risk and institute appropriate interventions to reduce falls and related injuries.

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