Prostate drug may slow Parkinson's disease

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The medicine, normally used for enlarged prostates, appears to slow the progression of Parkinson's, scientists have found.

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Existing Parkinson's treatments can help with some of the symptoms but can't slow or reverse the loss of neurons that occurs with the disease. They studied 2,880 Parkinson's patients taking terazosin or similar drugs that target PGK1 and a comparison group of 15,409 Parkinson's patients taking a different treatment for BPH that had no action on PGK1.

"That's a terrible state, because as our population ages Parkinson's disease is going to become increasingly common.Given that terazosin has a proven track record for treating BPH, he says, getting it approved and"repurposed" as a Parkinson's drug should be achievable if the clinical trials go well.

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