Vaccines, Science, Coronavirus

Vaccines, Science

Nowhere left for Covid to go to mutate into a deadly variant, says Oxford vaccine creator

🦠Dame Sarah Gilbert said Covid-19 will eventually become like other seasonal coronaviruses which cause the common cold

9/22/2021 10:23:00 PM

🦠Dame Sarah Gilbert said Covid-19 will eventually become like other seasonal coronaviruses which cause the common cold

Viruses tend to become less virulent over time as they spread through a population becoming more immune, according to Dame Sarah Gilbert

Dame Sarah Gilbert said that viruses tend to become less virulent over time as they spread through a population which is becoming more immune.Although Dame Sarah said some genetic drift was to be expected, she said Covid-19 will eventually become like other seasonal coronaviruses which cause the common cold and respiratory infections.

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Speaking on a Royal Society of Medicine webinar about variants on Wednesday, Dame Sarah said: “The virus can’t completely mutate because its spike protein has to interact with the ACE2 receptor on the surface of the human cell, in order to get inside that cell.

“If it changes its spike protein so much that it can’t interact with that receptor, then it’s not going to be able to get inside the cell. So there aren’t very many places for the virus to go to have something that will evade immunity but still be a really infectious virus.”

She added: “We normally see that viruses become less virulent as they circulate more easily and there is no reason to think we will have a more virulent version of Sars-CoV-2.“We tend to see slow genetic drift of the virus and there will be gradual immunity developing in the population as there is to all the other seasonal coronaviruses. There are four of them and they’ve been circulating for decades and we’re not even aware of them.

“So we already live with four different human coronaviruses that we don’t really ever think about very much and eventually Sars-CoV-2 will become one of those. The question of how long it’s going to take to get there and what measures we’re going to have to take to manage it in the meantime.”

So far, virus variants which looked like they might be more virulent and evade immunity have been out-competed by the delta variant, which is far more infectious.Keeping an eye on beta and lambda variants Experts are still concerned about the beta and lambda variants, but neither has ever managed to get a strong foothold in Britain.

Prof Sharon Peacock, the director of the Covid-19 UK Genomics Consortium, which monitors variants for the Government, also told the webinar: “It’s watch and wait, but delta is top of the list and other variants are not particularly concerning at the moment.

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“It has been pretty quiet since delta emerged and it would be nice to think there won’t be any new variants of concern. If I was pushed to predict, I think there will be new variants emerging over time and I think there is still quite a lot of road to travel down with this virus.”

Prof Peacock said that it was important to genetically sequence people who became ill after travelling to check that new variants were not being imported into Britain as they were the “canary in the coal mine”.However, she said that vaccinating as many people as possible around the world was the best way to prevent the emergence of worrying mutations.

“If we don’t vaccinate people and there is uncontrolled transmission and infection, then that is the right training ground for the virus to really emerge. That is a real variant of concern,” she added.“If we don’t have very much infection, then the virus doesn’t have much chance to mutate. So vaccination of the world is not only the morally right thing to do, but the strategically right thing to do if we are going to protect the world. Sequencing travellers are the canary in the coal mine as they will be where new variants are emerging.”

Prof Peacock also said she had not completely ruled out that the virus had been engineered or had leaked from a lab.“There is reason to think the virus did emerge from an animal host,” she said. “I haven’t seen any definitive evidence it is an engineered virus or escaped. But what this virus has taught me is to be humble when I’m wrong, and I’ve been wrong quite a few times and have had to become nimble in changing my mind.

Read more: The Telegraph »

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Enorme profesora. Yaaaaarb 🤲 Covid finding itself in a cul-de-sac!!! Nice.. She needs to keep shouting this. Keep repeating it on every news channel. Next briefing the press need to bring this up with Whitty and his crew. AllisonPearson Pure conjecture. Evidence supporting claims Covid will evolve to be less virulent? being Zero! How virulence will evolve is uncertain, it may evolve toward high virulence and wipe us out. Investigative evolutionary rule that viruses must become less virulent.

I think this very clever woman is quite disturbed at the direction this is going in. She doesn’t support boosters and I think wasn’t big on jabbing under 50s. Happy to be corrected. EVENTUALLY - and only after every single person on the planet is vaccinated not just old white male pale stale ones who speak English

It is the common cold

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