"The assumption has been that liver failure patients who continue to use alcohol are poor transplant candidates because they aren't motivated to take care of the donor organ," said senior author Brian Lee, a liver transplant hepatologist at Keck Medicine of USC."However, that view is not supported by the data."while screening potential transplant candidates for those most likely to thrive.
For example, many centers mandate six months of sobriety before transplantation, even though research shows such abstinence is no guarantee against post-transplant drinking. Doctors also view strong support networks as a plus when evaluating transplant candidates, though research hasn't confirmed the importance of that factor.USC does not mandate six months of sobriety. Such a delay in transplantation can be afor some patients, Lee said.
"With the extraordinary rise in both listings and completed transplants for alcohol-associated hepatitis in the setting of the COVID-19 pandemic, the need to explore the appropriateness of selection criteria is more relevant than ever," Lee said."This study will ideally serve as a foundation for ongoing debate among liver transplant providers and teams to improve selection and post-transplant practices as well as encourage a revision to national transplant policies.
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