By Surbhi JainAug 15 2022Reviewed by Susha Cheriyedath, M.Sc. In an article recently published in the journal ACS Chemical Neuroscience, researchers discussed the attenuation of paraquat -induced neuronal compromise in vitro and in vivo by carbon quantum dots derived from citric acid .
Applications of PQ in the Treatment of Neurodegenerative Diseases The agricultural and xenobiotic agent PQ, which is used as a herbicide in the cultivation of crucial crops, including soy, corn, and cotton, is of particular relevance. A rising range of neurodegenerative disorders, including Parkinson's disease , has been related to research on PQ.
Utility of Citric Acid-Sourced Carbon Quantum Dots In this study, the authors assessed the neuroprotective effects of citric acid-sourced carbon quantum dots on PQ-insulted human neuroblastoma-derived SHSY5Y cell lines and on a nematode that had been exposed to paraquat . According to the study, Cit-carbon quantum dots were a potentially useful bio-based nanomaterial that can be produced using green chemistry to treat neurodegenerative diseases.
Neuroprotective Effects of Cit-Sourced Carbon Quantum Dots The size of the Cit-CQDs ranged from 10 to 60 nanometers. A wide peak in the ultraviolet –visible spectrum at 330 nanometers indicated the presence of conjugated moieties capable of photoluminescence. The presence of oxidized groups and conjugated centers , which validated the solubility and photoluminescence capabilities of Cit-CQDs, was demonstrated by the infrared spectrum.
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