This Phase 1 trial is being carried out in the United States among 56 healthy adults who are HIV negative.
But hopes have been stirred with the success of mRNA technology, which allowed for the development of Covid-19 vaccines in record time, including one from Moderna. The vaccine is supposed to teach B lymphocytes, which are part of the immune system, to generate these antibodies. "Further immunogens will be needed to guide the immune system on this path, but this prime-boost combination could be the first key element of an eventual HIV immunization regimen," said Dr David Diemert, a lead investigator at one of the four sites where the trial is being carried out, George Washington University in the US capital.
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