NEW YORK: Novartis AG said on Wednesday it replaced the two top research and development executives at its Avexis unit after some data was manipulated from early testing of a gene therapy for infants that costs more than US$2 million.
The Swiss drugmaker said last week that it was in the process of"exiting" the Avexis scientists responsible for the manipulation of data on gene therapy Zolgensma. A Novartis spokesman said on Wednesday that a few other scientists beyond the Kaspars were no longer at the company but did not give any further details.The U.S.
Novartis said last week that it learned of allegations of data manipulation in mid-March and finished a preliminary investigation into the allegations in early May, confirming data discrepancies and raising data integrity concerns. Novartis acquired Avexis last year, paying US$8.7 billion for the maker of the rare-disease treatment, which is expected to bring in billions of dollars in sales.
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