Moderna said the results were a good sign for the company's plans for future shots targeting two Covid-19 variants.
Dr Jacqueline Miller, a top Moderna scientist, said the company had no immediate plans to file for authorisation of the bivalent vaccine including the Beta variant. It will submit the data to the United States Food and Drug Administration in order to lay the groundwork for a future bivalent vaccine candidate that includes the Omicron variant as a target.
The company said the bivalent vaccine with Beta generated higher neutralizing antibody titers against the Omicron variant at one and six months after the shot was given than the booster of its original vaccine currently in use. The company said it was especially encouraging that the bivalent vaccine induced higher antibody responses against variants that were not specifically included in the vaccine.Moderna has started testing a different bivalent shot that combines an Omicron-specific vaccine with its original. Initial data from that vaccine is expected later in the second quarter, Moderna said."In order to be ready for the fall, we've had to start manufacture at risk," Dr Miller said.
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