Many people think of melatonin as a natural nod-off aid, kind of like chamomile tea in pill form. Even the name of the popular dietary supplement sounds sleepy – that long “o” sound almost makes you yawn mid-word. But melatonin is also a hormone that our brains naturally produce, and hormones, even in minuscule amounts, can have potent effects throughout the body.
“Melatonin is sometimes called the ‘hormone of darkness’ or ‘vampire hormone,’” because it comes out at night, said Matthew Walker, a professor of neuroscience and psychology at the University of California, Berkeley, and the author of the book Why We Sleep. As levels of melatonin rise, levels of cortisol, the stress hormone, fall. Respiration slows. Soon, our eyelids begin to droop.
Melatonin may make you feel a little drowsier when you take it, but it has a bigger impact on regulating the timing of your overall sleep-wake cycle and helping to set the circadian clock, the roughly 24-hour internal timekeeper that tells your body what time of day it is and syncs it with the outside world.“The impact it has on our sleep depends on the time of day that you take it,” said Dr Martin, who is also a spokeswoman for the American Academy of Sleep Medicine.
Many experts recommend starting with the smallest available dosage – 0.5 milligrams to 1 milligram, 30 minutes to an hour before bedtime – and seeing how you do from there. If that has no effect, the dose can be gradually increased. “Compared to most other sleeping pills, the side-effect profile is much better,” and it’s not going to be addictive, said Dr Bhanu Prakash Kolla, an associate professor of psychiatry and a consultant at the Center for Sleep Medicine at the Mayo Clinic. But because melatonin can cause drowsiness, the Mayo Clinic warns that you shouldn’t drive or operate machinery within five hours of taking it.
“They’re trying to tell you when to take the melatonin so your body knows: ‘Oh, it’s dusk where I’m going,’” Dr Rosen said, explaining how you can use the supplement before your trip to readjust your body clock.Like other dietary supplements, melatonin is not regulated by the Food and Drug Administration, which means there may be wide variation among products.
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