JAKARTA - The Chinese, regional and global situation with regard to the new coronavirus, Covid-19, remains worrisome.
As the world lingers in crisis, global bioinformaticians, especially the Chinese, are trying their best to win the humanitarian and scientific battle against the deadly pathogen. The protease structure is attached with the N3 inhibitor and this is crucial information for the drug development effort. The sequence is a starting point in developing drugs, diagnostic tools and a vaccine for the dangerous virus.
Based on recommendations from scientists from the Public Health Clinical Center at Fudan University, China, utilising existing drugs lopinavir or ritonavir, for instance, could be a viable option, although it should be tested in clinical trial. However, in the present emergency situation, quicker alternatives to peer-reviewed scientific journals are needed as disseminators of research results. Life sciences preprint servers bioRxiv and medRxiv, for instance, have played their role well as databases of open science to hasten the dissemination of research results in a time of emergency.
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