Two molecules associated with high stress levels have been implicated in the development of broken heart syndrome, a condition that mainly affects post-menopausal women and is usually brought on by severe stress, such as the loss of a loved one.
Affecting an estimated 2,500 people in the UK each year, the syndrome also carries a risk of complications similar to that of an actual heart attack. It is unclear what causes takotsubo, but sharp spikes in adrenaline caused by acute stress like bereavement, car accidents, earthquakes and even happy events such as weddings are understood to drive loss of movement in part of the heart wall, which then precipitates the acute heart failure.
Overall, the findings appeared to link long-term stress and the dramatic takotsubo response to a sudden shock.
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