Fasting protects against food poisoning, mouse study suggests

7/8/2021 5:00:00 PM

Restricting your calorie intake to set windows – like the popular 5:2 diet – may boost gut bacteria.

Food Poisoning, Intermittent Fasting

Restricting your calorie intake to set windows – like the popular 5:2 diet – may boost gut bacteria .

The well-known 5:2 diet recommends eating normally for five days of the week and drastically cutting your calorie intake on the other two.

SalmonellaThis may seem counterintuitive, if you assume patients need nutritious food to boost their immune response."Whether this sickness behaviour has evolved as a protective mechanism is unclear", wrote the scientists., a common cause of food poisoning.

"rapidly expanded in the intestines of [the] fed mice".SalmonellaSalmonellaWatch: Fasting less effective than a calorie-controlled dietOverall, similar results also occurred with the food-poisoning bacteriaSalmonella

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Read more: While more research is required, restricting your calorie intake to set windows – like the popular 5:2 diet – may boost gut bacteria that prevent damaging bugs from invading the gastrointestinal tract. Salmonella bacteria are a common cause of food poisoning. It was first identified in Peru last year , and has since spread to other countries in South America and around the world. (Stock, Getty Images) "Most animals, including humans, lose their appetite when sick," the scientists wrote in the journal PLOS Pathogens. The plan was shelved after investors deemed its valuation too lofty. This may seem counterintuitive, if you assume patients need nutritious food to boost their immune response. That means it's suspected to be extra infectious or dangerous. Read more: Fasting lowers blood pressure in rats "Whether this sickness behaviour has evolved as a protective mechanism is unclear", wrote the scientists. Source: Reuters/zl.

With fasting becoming "popular in recent years", the team infected the mouths of mice that had either been fasting or eating as normal with the bacteria Salmonella enterica , a common cause of food poisoning. antibodies Three mutations in the spike protein of the virus may make the Lambda variant able to resist vaccine-induced antibodies, according to lab studies summarized in a recent preprint paper by Japanese researchers that has not yet been peer-reviewed.2170 ringgit) (Reporting by Liz Lee; Editing by Kenneth Maxwell) Source: Reuters. "Notably, the fasted mice were protected from infection," wrote the scientists. In contrast, the "rapidly expanded in the intestines of [the] fed mice". "Because the Lambda variant is relatively resistant to the vaccine-induced antisera (blood serum containing antibodies against specific antigens), it might be possible that this variant is feasible to cause breakthrough infection," the authors . Read more: "Moreover, Salmonella in the fasted mice did not cause any intestinal damage as the bacteria were unable to invade the intestinal wall," wrote the scientists. When the fasted mice were re-fed for one day after their eating was restricted, there was a "dramatic increase" in Salmonella numbers and their invasion into the intestinal wall, but to a lesser extent than the rodents who had eaten as normal. However, Dr.

Story continues Watch: Fasting less effective than a calorie-controlled diet The scientists also investigated the potential of fasting in a group of mice that "lacked a microbiome".  These animals "suffered less gastroenteritis" but still became unwell, highlighting how beneficial gut bacteria may provide "partial protection". Lambda is not uniformly dominating Three months ago in Chile, half of sequenced cases were of the Lambda variant, but that has dropped to around 23%, Soto Rifo said. Overall, similar results also occurred with the food-poisoning bacteria Campylobacter jejuni , revealing the findings are not Salmonella specific. "We therefore conclude fasting can protect hosts from intestinal bacterial infections, in part through the actions of the gut microbiome," wrote the scientists. Story continues "So we cannot say what's going to happen in other countries," Soto Rifo said. "When food is limited, the microbiome appears to sequester the nutrients that remain, preventing pathogens from acquiring the energy they need to infect the host.

  "While more research is needed, fasting or otherwise adjusting food intake could be exploited therapeutically to modulate infectious diseases in the future. Research in South America is needed to help the rest of the world understand this variant As of August 4, there had been." Watch: How to safely handle raw chicken TRENDING .